American Society

for Rickettsiology


SCIENTIFIC AGENDA         Digital Program w/ Abstracts  ASR reserves the right to substitute talks &/or speakers


SATURDAY JULY 13


 

AM

Free Time / Optional Pre-Meeting Activities:

 
12:00 - 5:30 PM REGISTRATION DESK OPEN Virginia Ballroom Foyer

12:00 - 3:00 PM

Poster Set Up

Virginia Ballroom EF

     
12:30 - 1:30 Trainee Lunch & Mixer Virginia Ballroom ABCD

1:30 – 2:30

Trainee Career Development Session

Moderator: Daniel Voth, Univ. of Arkansas

Panelists:  Minal Mulye, Karen Elkins, Lee Fuller, Steve Dumler, Stephanie Hannah

Virginia Ballroom ABCD

     
2:30 - 3:00 BREAK  
     

3:00 – 3:15 PM

Welcome & Introductions

   Stacey Gilk, ASR President

Virginia Ballroom ABCD

3:15 – 5:00 PM

Session 1: Epidemiology, Diagnostics, and Vaccine Development

   Session Chair: Kristin Mullins, Univ. of Maryland

 

3:15 PM 1A. Plenary: Karen Elkins, FDA - Correlates of protection for intracellular pathogens: Lessons from studying M. tuberculosis vaccination in genetically diverse mice  

3:45 PM

1B.  Keynote: Roman Ganta, Univ. of Missouri - Molecular Genetic Tools Broadly Applicable in Ehrlichia and Anaplasma species to Define Essential Genes and Vaccine Development

 

4:15 PM

1C.  Johanna Salzer - National Surveillance for Human Ehrlichiosis caused by Ehrlichia ewingii— United States, 2013–2021


4:30 PM

1D. Perle Latre de Late - Inactivated whole cell bacterial antigen vaccine protects dogs from Rocky Mountain Spotted Fever caused by Rickettsia rickettsii independent of adjuvants used


4:45 PM

1E. Karren Plain - Immunity in guinea pigs induced by a new Q-fever sub-unit vaccine based on the O-specific polysaccharide of virulent (phase 1) Coxiella burnetii




 

5:00 - 5:30 PM

BREAK

Virginia Foyer

     

5:30 – 6:30 PM

ASR LECTURE: "KIck Ass Women"

Kelly Brayton, Washington State University

Virginia Ballroom ABCD

 

 

 

6:30 – 8:00 PM

WELCOME RECEPTION & DINNER

Virginia Foyer & Lawn

     

SUNDAY JULY 14


 

7:30 - 8:30 AM

BREAKFAST BUFFET

Virginia Foyer

7:30 - 12:00 PM

REGISTRATION DESK OPEN

Virginia Foyer


 

 

8:30 – 10:15 AM

Session 2: New Genetic Tools for Rickettsia Workshop

   Session Chair:  Becky Lamason, MIT & Sam Perdue, NIH

This workshop will feature recent recipients of the R61/R33 RFA “Genetic Tools for Understanding Rickettsial and Related Infections” and will enable facilitated discussions with attendees around the challenges, approaches, and current and future needs of the field.

Panelists:

  • Paige Allen, Virginia Commonwealth University
  • Erin Goley - Johns Hopkins Medical Institute
  • Hwan Kim - Stonybrook University
  • Jason Park - Washington State University
  • Hema Prasad - University of Texas Medical Branch
  • Mary Weber - University of Iowa

Virginia Ballroom ABCD

 

 

 

10:15 – 10:30 AM

BREAK

Virginia Foyer



 

10:30 – 12:15 PM 

Session 3: Coxiella Biology and Pathogenesis

   Session Chair: Carrie Mae Long, NIH

Virginia Ballroom ABCD

10:30 AM

3A. Plenary Lecture: Shumin Tan, Tufts University -Illuminating the integration of Mycobacterium tuberculosis environmental cue response with its metabolism

 

11:00 AM

3B. Keynote: Anders Omsland, Washington State University Coxiella: Metabolic Drivers of Virulence

 

11:30 AM

3C. Nicole Ellis - Innovations in Multiplex CRISPRi Promote the Identification of Virulence Critical Genes in Legionella


11:45 AM

3D. Het Adhvaryu - PERK-Dependent Mitochondrial Re-Programming of Human Alveolar Macrophages by Coxiella burnetii


12:00 PM

3E. Zi Yang - Identification of a Coxiella burnetii porin required for intracellular replication


 

 

 

12:15 – 1:15 PM

Lunch & ASR Power Hour (included)

Virginia Ballroom EF

   
1:15 - 2:45 PM Poster Session 1 (Odd numbers)  


 

Afternoon

Free Time / Optional Group Excursion

Dinner on your own - View CWB Dining options


     
     

MONDAY JULY 15


 

7:30 - 8:30 AM

BREAKFAST BUFFET

Virginia Foyer

7:30 - 3:30 PM

REGISTRATION DESK OPEN  

Virginia Foyer

 

 

 

8:30 – 10:15 AM

Session 4: Cell Biology of Infection

   Session Chair: Yuejin Liang, Univ. of Texas Medical Branch

Virginia Ballroom ABCD

8:30 AM

4A.  Plenary Lecture: Isabelle Derre, Univ. of VA - How to make contact: A tale for three Chlamydia inclusion membrane proteins

 

9:00 AM

4B. Keynote: Ted Hackstadt, NIH - The search for virulence determinants in spotted fever group rickettsia

 

9:30 AM

4C. Thomas Siff - A conserved domain in multiple Orientia tsutsugamushi Ank effectors is critical for modulating NF-κB


9:45 AM

4D. Rajendra Angara - CbEPF1’s molecular mimicry to manipulate host inter-organelle contact sites and host lipid droplet metabolism


10:00 AM

4E. Sergio Lopez-Madrigal - Macromolecular tricks of a ubiquitous Anaplasmataceae



 

 

10:15 – 10:30 AM

BREAK

Virginia Foyer




10:30 - 12:00 PM  Poster Session 2 (Even numbers)  
     
12:00 - 1:15 PM 

ASR Lunch (included)

Virginia Ballroom EF
     

1:15 - 3:00 PM 

Session 5: Host Immune Response Against Rickettsial Pathogens

   Session Chair: Erin van Schaik, Texas A&M University

Virginia Ballroom ABCD

1:15 PM

5A: Plenary Lecture: Sunny Shin, Univ. of Pennsylvania

 

1:45 PM

5B: Keynote: Joe Pedra, Univ. of Maryland - Immune-Epithelial Interactions During Tick-Borne Pathogen Transmission

 

2:15 PM

5C. Oliver Voss - Pathogenic rickettsiae utilize the phosphatidylserine binding receptor, CD300f on macrophages for host invasion and pathogenesis


2:30 PM

5D. Casey Gonzales - Orientia tsutsugamushi Karp vs. Gilliam Strains Elicit Differential Humoral Immune Responses in Mice


2:45 PM

5E. Sean Riley - Genetic and Immunological Correlates of Susceptibility of Resistance to Rickettsia conorii Infection


 

 

 

3:00 – 3:30 PM

BREAK

Virginia Foyer




3:30 PM – 5:15 PM

Session 6: Biology of Anaplasma and Ehrlichia

   Session Chair: Jason Park, Washington State University

Virginia Ballroom ABCD

3:30 PM

6A: Plenary Lecture: Matt Lawrenz, Univ. of Louisville - Distinct Mechanisms of T3SS Recognition Control Leukotriene B4 Synthesis in Neutrophils and Macrophages

 

4:00 PM

6B. Keynote: Nahed Ismail, Univ. of Illinois Chicago- Exploiting Cell Death Pathways in Ehrlichiosis for Novel Therapeutics

 

4:30 PM

6C. Jason Park - Anaplasma phagocytophilum shifting gears in the tick vector


4:45 PM

6D. Omid Teymournejad - Hepatocyte-Specific HMGB1-mediated inflammation and Cell Death Promotes Ehrlichia-induced Acute Liver Injury

 

5:00 PM

6E. Andres Londono - Antimicrobial and innate immune coordinating functions of type I and II interferons in A. phagocytophilum infection





5:20 PM - 6:20 PM ASR Business Meeting  Virginia Ballroom ABCD
     

7:00 PM - 9:30 PM

ASR GROUP DINNER at Shields Tavern (incl. reg. attendee & guests)

Meet in hotel lobby at 7:00
     

TUESDAY JULY 16


 

7:30 - 8:30 AM

BREAKFAST BUFFET

Virginia Foyer

8:00 - 10:30 AM

REGISTRATION DESK OPEN


 

 

 

8:30 – 10:15 AM

Session 7: Vector Contribution to Rickettsial Pathogenesis

   Session Chair: Tais Saito, NIH

Virginia Ballroom ABCD

8:30 AM

7A:  Plenary Lecture: Monika Gulia-Nuss, Univ. of Nevada - Genome-editing to Combat Ticks and Tick-borne Disease

 

9:00 AM

7B.  Keynote: Susan Noh, USDA - From macro to micro: working across scales to understanding the tick-pathogen partnership

 

9:30 AM

7C.  Sujata Chaudhari - Shaping the Shield: Exploring Tick Cuticle Remodeling


9:45 AM

7D.  Hanna Laukaitis - Functional and molecular characterization of hemocytes inIxodes scapularis


10:00 AM

7E.  Dana Shaw - Bridging the Gap: UPR-IMD pathway connections revealed through APEX2 proximity proteomics in ticks


 

 

 

10:15 - 10:30 AM

BREAK

Virginia Foyer



 

10:30 – 12:15 PM 

Session 8:  Tick-borne Rickettsia

   Session Chair: Hwan Kim, SUNY Stonybrook

Virginia Ballroom ABCD

10:30 AM

8A. Plenary Lecture: Ken Fields, Univ. of Kentucky - Genetic manipulation of obligate intracellular bacteria—lessons learned from Chlamydia

 

11:00 AM

8B. Keynote Speaker: Erin Goley, Johns Hopkins - Quantitative cell biology of Rickettsia parkeri

 

11:30 AM

8C. Adam Nock - RoaM affects the transcription of several putative effectors inRickettsia rickettsii governing the transition to a cellular program of active spreading


11:45 AM

8D. Hannah Margolis - Answering a century-old riddle: SFG Rickettsiae enter host nuclei through nuclear envelope protrusions using actin-based motility


12:00 PM

8E. Luke Helminiak - Biological roles of a conserved rickettsial hemolysin, TlyC2, in Rickettsia-host-vector interactions


 

 

 

12:15 – 12:30 PM

Closing Remarks

Virginia Ballroom ABCD

Early Career Mentoring Session

This mentoring session will focus on different career paths, with a panel of scientists from academia, government, and industry meeting with students and postdoctoral trainees to discuss the transition process, challenges, and opportunities.

ASR Lecture

The ASR Lecture is given by a distinguished investigator that has made significant contributions to the field of rickettsial diseases. The lecturer frames past public health observations and/or scientific discoveries in the context of current research. The ASR lecture also provides the community with challenges and opportunities in the realm of basic, clinical, and translational research.

American Society for Rickettsiology

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