Open postdoctoral position in bacterial pathogenesis & host response.

A postdoctoral position investigating bacterial pathogenesis and the host innate immune response to infection is available in the Burke lab at the University of California, Irvine. We study intracellular pathogens that reside in the host cytosol, namely Rickettsia species. Key questions we are pursuing include: How do these obligate cytosolic pathogens evade antibacterial autophagy and killing by interferon-stimulated genes? What virulence factors promote their intracellular survival? And, why do humans develop disease while rodent reservoirs are resistant? These studies use a variety of molecular techniques, including confocal and super-resolution imaging, CRISPR-based mutations and screens in eukaryotic cells, forward genetic screens of bacterial mutants in vitro and in mice, cloning, mouse infections, flow cytometry, and development of new microbial genetic and imaging tools. See our recent publications and learn more about our research here: burkelab.medschool.uci.edu.

Candidates must hold a PhD degree and have experience related to microbiology or innate immunity.

UCI postdoc salary scales can be found here: https://ap.uci.edu/compensation/salary-scales/.

UCI provides below-market-rate on-campus housing for postdocs: www.pda.grad.uci.edu/resources/housing/

Our lab is in the Department of Microbiology and Molecular Genetics in the School of Medicine. Interested candidates should send their CV with contact information for three references to Dr. Thomas P. Burke, tpburke@uci.edu.